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53 Member Publications for October

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RCSB PDB AI Help Desk: retrieval-augmented generation for protein structure deposition support.
1. Bioinform Adv - published October 10, 2026
2. Chithari VR, Young JY, Persikova I, Liang Y, Crichlow GV, Flatt JW, Ghosh S, Hudson BP, Peisach E, Sekharan M, Shao C, Burley SK
Keratin filaments and soluble vimentin interact with isoform specificity to organize cell signaling.
1. Genes Dev - published October 9, 2026
2. Chouhan S, Boujemaa-Paterski R, Munawar S, Bhatt K, German Do Nascimiento L, Li A, Gałecki S, Rajendran D, Isogai T, Dean KM, Danuser G, Medalia O, Nanes BA
The IKK complex and TBK1/IKKε are recruited to STING through distinct mechanisms to activate NF-κB signaling.
1. Sci Immunol - published October 9, 2026
2. Christensen AH, Jurkiewicz AJ, Jensen CS, Kjøge K, Luo W, He W, Chen Y, Liu J, Dalskov L, Bagger AB, Winther KG, Gulstad KG, Lorentzen A, Haas G, Kamper JM, Stafford C, Gyrd-Hansen M, Enghild JJ, Hornung V, Cai H, Imler JL, Gad HH, Hartmann R
Temporal transcriptomics identifies transregulation by multiple lncRNAs in human iPSCs.
1. Genome Res - published October 9, 2026
2. Liu M, Mamede I, Sofi S, Pereira I, Dostal V, Pashos ARS, McMahon C, Waikar A, Stephenson G, Cech TR, Rinn JL
An integrated open-source acquisition and analysis ecosystem for high-throughput single-molecule imaging.
1. Nat Methods - published October 9, 2026
2. Terry DS, Kiselev R, Juette MF, Kilic Z, Brady RA, Sun Y, Blanchard SC
Drug-specific resistance mechanisms to RET inhibitors in RET fusion-positive NSCLC.
1. Clin Cancer Res - published October 8, 2026
2. Liu X, Paula AG, Nilsson MB, Cai L, He J, Huo X, Kumar A, Wang K, Yekeen A, Westover KD, Araujo HA, Heymach JV, Kittler R
Validation and analysis of 12,000 AI-driven CAR-T designs in the Bits to Binders competition.
1. Mol Syst Biol - published October 8, 2026
2. Kosonocky CW, Abel AM, Feller AL, Cifuentes Rieffer AE, Woolley PR, Lála J, Barth DR, Gardner T, Bits to Binders Competitors, Ekker SC, Ellington AD, Wierson WA, Marcotte EM
Scope and Differences between ACS Medicinal Chemistry Letters and Journal of Medicinal Chemistry.
1. ACS Med Chem Lett - published October 8, 2026
2. Chibale K, Lindsley CW
SNX17 facilitates entry and infection of Rift Valley fever virus and related bunyaviruses.
1. Cell Rep - published October 7, 2026
2. Ganaie SS, Fatma F, Hu Z, Grodzki M, Rush RE, Clees J, Brown G, Barreca O, Cui X, Cho BK, Goo YA, Hartman AL, Leung DW, Amarasinghe GK
Structural basis for regulating lipopolysaccharide transmembrane transport.
1. Nature - published October 7, 2026
2. Taylor RJ, Pahil KS, Caruso A, Plaman B, Early SA, Rowe SJ, Baidin V, Wilson A, Ruiz N, Walsh RM Jr, Harrison SC, Kahne D
Mechanism of spliceosome termination.
1. Nature - published October 7, 2026
2. Boreikaite V, Faraway R, Vorländer MK, Phillips AW, Opitz L, Wanke M, Yakoub G, Raffl G, Fin L, González-Prieto R, Luijsterburg MS, Ameres SL, Plaschka C
HelD is a global transcription factor enhancing gene expression in rapidly growing mycobacteria.
1. Microbiol Res - published October 7, 2026
2. Vaňková Hausnerová V, Kumar D, Neva S, Shoman M, Schwarz M, Modrák M, Jirát Matějčková J, Brázda P, Havelková J, Capdevila AC, Šiková M, Pospíšilová D, Halada P, Šanderová H, Holubová J, Dohál M, Převorovský M, Staněk O, Knejzlík Z, Kouba T, Dvořáková V, Hnilicová J
Cnidarian mechanosensory cells as ancestors of vertebrate hair cells: Molecular targeting of an ancient mechanotransduction complex.
1. Proc Natl Acad Sci U S A - published October 6, 2026
2. Banday ZZ, Randich AM, Hulse RE, Tong Z, Havrilak JA, Osorno-Ferro T, Watto E, Demchenko EA, Fournier Z, Grillet N, Sotomayor M, Layden MJ, Malamy J, Perozo E
PKD2-like proteins target Chlamydomonas PKD2 to distinct subciliary regions.
1. Proc Natl Acad Sci U S A - published October 6, 2026
2. Das P, Zhou H, Sureshkumar S, Chasen N, Dai J, Brown A, Lechtreck K
Mechanisms of substrate recognition and catalysis in a mammalian phosphatidylserine synthase 2.
1. Proc Natl Acad Sci U S A - published October 6, 2026
2. Wang L, Zhang Z, Yang H, Laganowsky A, Zhou M
LAT condensation gates PLCγ1 activation via bimodal LAT phosphorylation.
1. Proc Natl Acad Sci U S A - published October 6, 2026
2. Ren H, Lee HR, Omar YAD, DeGrandchamp JB, Hung CL, Eisen TJ, Stamou D, Kuriyan J, Chakraborty AK, Groves JT
The mycomembrane proteins PorH and ProtX are inserted at polar growth zones and linked to the cell wall.
1. Proc Natl Acad Sci U S A - published October 6, 2026
2. Hart EM, de Bruin DA, Marando VM, Arnau Alemany M, Snow ED, Schultz BJ, Kuru E, Walker S, Vettiger A, Bernhardt TG
Nuclear prohibitin 1 depletion drives alcohol-associated liver injury and sensitization to colon cancer liver metastasis.
1. J Clin Invest - published October 6, 2026
2. Chhimwal J, Sinha S, Kim J, Alba M, Barbier-Torres L, Wang J, Yang H, Lim Y, Murali R, Tomasi ML, You S, Mato JM, Lu SC
Late effects after novel therapies for childhood cancer: Anticipating the future landscape of health outcomes for survivors.
1. J Natl Cancer Inst - published October 6, 2026
2. Berkman AM, Teachey DT, Ehrhardt MJ, Pui CH, Inaba H, Karol SE, Castellino SM, Dixon SB, Yang JJ, Gross TG, Federico SM, Packer RJ, Pappo AS, Qaddoumi I, Salloum R, Smith SM, Cooper T, Henderson TO, Hawkins DS, Nathan PC, Chow EJ, Fox E, Armstrong GT
SPARCS enables scalable recovery of complex image-based phenotypes for genetic screening.
1. Cell - published October 6, 2026
2. Schmacke NA, Mädler SC, Wallmann G, Metousis A, Varlamova V, Steigerwald S, Christ SB, Bérouti M, Harz H, Leonhardt H, Theis FJ, Mann M, Hornung V
Genomic drivers of leukemia and blinatumomab response in adult acute lymphoblastic leukemia - the ECOG-ACRIN E1910 study.
1. Blood - published October 5, 2026
2. Zhong X, Roberts KG, Wei H, Sun Z, Montefiori LE, Kumar A, Iacobucci I, Baviskar P, Gao Q, Pölönen P, Pruett-Miller SM, Schreiber RM, Chang TC, Zhang W, Lei S, Rampersaud E, Fan Y, Wu G, Mattison RJ, Zhang Y, Racevskis J, Lazarus HM, Rowe JM, Arber DA, Wieduwilt MJ, Abou Mourad Y, Shami PJ, Baer MR, Asch AS, O'Dwyer KM, Hall A, Liedtke M, Bergeron J, Wood BL, Pratz KW, Dinner SN, Frey NV, Gore SD, Bhatnagar B, Atallah EL, Uy GL, Jeyakumar D, Lin TL, Willman CL, Podoltsev NA, DeAngelo DJ, Patel S, Elliott MA, Advani AS, Tzachanis D, Vachhani P, Bhave RR, Sharon E, Little RF, Erba HP, Stone RM, Tallman MS, Yang JJ, Luger SM, Paietta E, Litzow MR, Mullighan CG
Differential formation of nitrate-responsive mycobacterial intracytoplasmic membranes during Mycobacterium tuberculosis infection.
1. Cell Rep - published October 5, 2026
2. Keck C, Tachon S, Sayes F, Musiani D, Gianetto QG, Matondo M, Vos M, Brosch R, Enninga J
Near-atomistic simulations reveal the molecular principles that control chromatin structure and phase separation.
1. Nat Commun - published October 3, 2026
2. Russell K, Chen Y, Espinosa JR, Farré-Gil D, Zhou H, Maristany MJ, Perez-Lopez JI, Huertas J, Orozco M, Rosen MK, Collepardo-Guevara R
Transposon end recognition and pairing by I-F3 CRISPR-associated transposase.
1. Sci Adv - published October 2, 2026
2. Truong VH, Miller DJ, Fatma S, Sheng Y, Pindi C, Ahsan M, Palermo G, Kellogg EH
Distinct allosteric remodeling of HIV-1 Env dynamics on virions by gp41-directed antibodies reveals two modes of neutralization.
1. Elife - published October 2, 2026
2. Xu W, Gonepudi NK, Liu J, He Y, Katte R, Wang R, Awuah HB, Han Y, Zhang B, Yu J, Hu B, Ho DD, Acharya P, Kwong PD, Lu M
Deacetylation degree modulates interfacial interactions and delivery performance of konjac glucomannan-soy protein microcapsules for encapsulating Zanthoxylum bungeanum essential oil.
1. Food Res Int - published October 1, 2026
2. Pan Y, Zeng Z, Fan J, Zhou M, Lu M, Chen Z, Rao C, Liu X
Separating the effects of temperature and absorbed X-ray dose on unit-cell volume.
1. Acta Crystallogr D Struct Biol - published October 1, 2026
2. Southworth-Davies RJ, Murray JW, Carmichael I, Rudiño-Piñera E, Weik M, Garman EF
Phage proteases activate CBASS antiphage immunity.
1. Science - published October 1, 2026
2. Hobbs SJ, Kranzusch PJ
Molecular glue everywhere: Metabolites join the party.
1. Mol Cell - published October 1, 2026
2. Wang B, Zheng N
Conserved and divergent mitochondrial assemblies in kinetoplastid parasites.
1. Mol Cell - published October 1, 2026
2. Solayman M, Liao YT, Calvo SE, Vacas AF, Papanastasiou M, Rivera KD, Mani DR, Boyle BW, Deng FG, MitoCarta Tree of Life Consortium, Udeshi ND, Mootha VK, Aphasizheva I, Chao LH, Aphasizhev R
Mitochondrial proteome of Acanthamoeba delineates aerobic and anaerobic pathways dynamically regulated by oxygen.
1. Cell - published October 1, 2026
2. Stefely JA, Deng FG, Chen MZ, Nguyen K, Luce BE, Fry MY, Guo XA, Maliaris K, Rivera KD, Papanastasiou M, Issa TM, Kanakapura Sundararaj B, Root SLY, Mani DR, MitoCarta Tree of Life Consortium, Chao LH, Calvo SE, Udeshi ND, Samuelson J, Mootha VK
A high-confidence inventory of the proteins in the mitochondrion-related organelle of Giardia.
1. Curr Biol - published October 1, 2026
2. Goyal M, Issa TM, Stefely JA, Venkatraman K, McCoy JG, Lam SS, Chen MZ, Nguyen K, Lian CG, Jean-Beltran PM, Fry MY, Luce BE, MitoCarta Tree of Life Consortium, Chao LH, Carr SA, Udeshi ND, Calvo SE, Mootha VK, Samuelson J
Mitochondrial proteome of the apicomplexan Babesia divergens.
1. Curr Biol - published October 1, 2026
2. Betsinger CN, Calvo SE, Mian SY, Bauer NC, Paul AS, Batzli DL, Lian CG, Boyle BW, Rivera KD, Sreenivasamurthy SK, McCoy JG, Chen MZ, Issa TM, Stefely JA, MitoCarta Tree of Life Consortium, Dvorin JD, Udeshi ND, Duraisingh MT, Mootha VK
Acanthamoeba ATP synthase structure reveals the TCA cycle is tethered to OXPHOS.
1. Cell - published October 1, 2026
2. Fry MY, Luce BE, Stefely JA, Chen MZ, Deng FG, Issa TM, MitoCarta Tree of Life Consortium, Calvo SE, Samuelson J, Mootha VK, Chao LH
The CUP pilus SMF-1 utilizes a specific antiparallel bundling mechanism to initiate biofilm formation.
1. Cell Rep - published October 1, 2026
2. Fields JL, Sebastian CC, Zhang H, Bhaumik R, Zia A, Robertson AN, Anderson GG, Mattoo S, Wu H, Kiedrowski MR, Wang F
Protocol for brain and ventricle volume comparison after clearing and light-sheet microscopy in mice.
1. STAR Protoc - published October 1, 2026
2. Blas-Medina A, Phan MS, Ali-Moussa S, Spassky N, Fernandes J, Tinevez JY, Deczkowska A, Travier L
QuickProcess2: an integrated package for crystallography data visualization, processing and management at the GM/CA Structural Biology Facility.
1. J Appl Crystallogr - published October 1, 2026
2. Xu Q, Hilgart MC, Venugopalan N, Kissick D, Becker M, Xu S, Makarov O, Stepanov S, Smith JL, Fischetti RF
Inducible dCas12a system expands CRISPRi/a capabilities for functional genomics in malaria parasite Plasmodium falciparum.
1. iScience - published October 1, 2026
2. Lucky AB, Li X, Kobakhidze G, Gonzales JL, Wang C, Cui L, Dong G, Miao J
Extended local deuteration of leucine enhances methyl NMR of large proteins expressed in eukaryotic cells.
1. Chem Commun (Camb) - published October 1, 2026
2. Schindler S, Dubey A, Mallis RJ, Radeva DL, Georgieva NG, Burdzhiev NT, Knödlstorfer S, Reinherz EL, Gelev VM, Arthanari H
Molecular mechanism of KRAS binding to BRAF and its regulation by the BRAF-specific region.
1. Structure - published October 1, 2026
2. Bonsor DA, Sandin Lawrence SI, Tran TH, Swain M, Dharmaiah S, Mehalko J, Messing SA, Nissley DV, McCormick F, Stephen AG, Simanshu DK
Product-stabilized filamentation by human glutamine synthetase allosterically tunes metabolic activity.
1. Elife - published October 1, 2026
2. Greene E, Muniz R, Yamamura H, Hoff SE, Bajaj P, Tecson MCB, Geluz C, Lee DJ, Thompson EM, Arada A, Lee GM, Bonomi M, Kollman JM, Fraser JS
Structural basis and rational engineering of a thermophilic Cas13a for robust RNA detection.
1. Cell Chem Biol - published October 1, 2026
2. Oladeji SJ, Gonzalez DH, Deng X, You Z, Zhang Y, Golla DA, Smith J, Zhang Y, Gao X, Lillehoj PB, Gao Y
Structural basis of directionality control in large serine integrases.
1. Mol Cell - published October 1, 2026
2. Shin H, Pigli Y, Peña Reyes T, Bello AJ, Taiwo-Aiyerin OT, Fuller JR, Olorunniji FJ, Rice PA
Noncoding RNAs in Cancer: Functions, Mechanisms, and Targeting Approaches.
1. Annu Rev Pathol - published October 1, 2026
2. Montero JJ, Braun CJ, Sattler M, Rad R
Mitochondrial stress induces transcription of cytosolic and mitochondrial protein synthesis components via NHR-180.
1. Cell Rep - published October 1, 2026
2. Mallick A, Ramalho T, Ali L, Du Y, Hoang D, Li R, Rai P, Kim S, Ahsan R, Shaqra AM, Bergmann A, Schiffer CA, Zhu LJ, Kelch B, Shen K, Haynes CM
1,3-Dioxolane derived nucleos(t)ides: synthetic strategies, current position, and future promise in antiviral and anticancer drug discovery.
1. Med Chem Res - published October 1, 2026
2. Gudi M, Estes J, Kothapalli Y, Sarafianos SG, Singh US
NCCN Guidelines® Insights: Hepatocellular Carcinoma, Version 2.2026.
1. J Natl Compr Canc Netw - published October 1, 2026
2. Benson AB 3rd, D'Angelica MI, Ahmed A, Akce M, Anaya DA, Anders R, Are C, Aye L, Bachini M, Baker M, Binder D, Burgoyne A, Castellanos J, Chokshi S, Cleary J, Cloyd J, Cullinan D, Dendy Case M, Franses J, Goyal L, Harris W, Jennings L, Kelley RK, Khan S, Krishnan M, Levine M, Melstrom L, Palta M, Raman S, Ronnekleiv-Kelly S, Sahai V, Stephans K, Thanikachalam K, Turk A, Vauthey JN, Venook AP, Wo J, Yano M, Yopp A, Zhao K, Hochstetler C, Schonfeld R, Stein M
Atomic, structural and molecular insights into GPCR ligand binding and signalling.
1. Nat Rev Mol Cell Biol - published October 1, 2026
2. Nemec K, Mészáros B, Skiniotis G, Blanchard SC, Babu MM
A structurally defined nucleoplasmic-facing surface of Nup170 controls subtelomeric gene silencing.
1. Mol Biol Cell - published October 1, 2026
2. Choudhry SK, Neal ML, Saik NO, van Eeuwen T, Sariki SK, Li S, Mast FD, Wozniak RW, Rout MP, Aitchison JD
SPRIZ (CCDC127) protein conserved in deuterostome animals is a rigid OMM-IMM tether that locally sets mitochondrial IMS volume.
1. Sci Adv - published October 1, 2026
2. Shulinski R, Loban R, Farhat D, Cartes-Saavedra B, Magda MJ, Kotchetkov P, Caminiti V, David L, Wolf YI, O'Dwyer C, Fullerton M, Burelle Y, Lee JE, Raimondi A, Koonin EV, Hajnóczky G, Harper ME, Pellegrini L
Variant escape site mapping and characterization of SARS-CoV-2 nucleocapsid rapid antigen test antibodies.
1. J Virol - published October 1, 2026
2. Keith AD, Keen MM, Frank F, Lam WA, Greenleaf M, Ortlund EA
In vivo engineering of CAR natural killer cells for immunotherapy using ligand-directed lipid nanoparticles.
1. Nat Biotechnol - published October 1, 2026
2. Chen Y, Monkovic J, Mughal H, Chen B, Thadhani E, McMullen P, Self A, Chen Y, Hu Y, Detmer S, Chen M, Lapteva A, Kamat R, Vernon A, Langer R, Anderson DG
A B1 SINE element within the mouse Malat1 long noncoding RNA acts as an internal ribosome entry site mediating micropeptide translation.
1. Sci Adv - published October 1, 2026
2. Xiao W, Hann T, Perry Z, Pandey V, Cheng J, Wohlschlegel J, Pyle AM, Black DL